A woman in her late fifties has been killed after a motorbike collision on Tuesday night in Amersham Road, New Cross.
The motorbike had collided with a car around 10pm before hitting two pedestrians, the woman was taken to hospital in a critical condition but died a few hours later.
The other male pedestrian involved was treated for minor injuries.
The male motorcyclist and the driver of the car involved in the initial collision were taken to hospital where they were treated for minor injuries.
Temporary road closures are in place.
Anyone with information or dash-cam footage concerning the collisions is asked to call police on 101 quoting CAD 8263/06Aug or Crimestoppers anonymously via 0800 555 111.