Brixton Hill, in Brixton, has been closed just after midday, today, after a stabbing on the busy road.
A Met Police spokesperson said: “Police were called at 12.07pm on Thursday, August 29 to reports of a stabbing.
“Officers, London Ambulance Service (LAS) and London’s Air Ambulance attended.
“At the scene, a male had suffered a stab wound.”
The victim, 39, was rushed to a south London hospital. He was pronounced dead shortly after. Police say his next of kin have been informed and a post-mortem will be scheduled in due course.
Two males have been arrested on suspicion of attempted murder.
The police spokesman added: “They have been taken to a south London police station where they remain at this time.
“At this early stage officers retain an open mind as to motive.”
A crime scene and road closures remain in place while police invesigate.
Traffic is said to be queuing following the closure between the South Circular and Upper Tulse Hill.
A total of 12 bus routes – 45, 57, 59, 109, 118, 133, 137, 159, 201, 250, 333 and 417 – are now on diversion following the incident.
If you have any information from the scene, please contact our news reporters by emailing email@example.com or by calling 03300 580 680 (Option 4). Anyone who witnessed this incident or has information should call 101 quoting 3334/29AUG, Tweet @MetCC or call Crimestoppers anonymously on 0800 555 111.